Cannabis and causality — using multiple methods to unpick links between cannabis and neurobiology, cognition and mental health
Although cannabis’ legal status varies, globally it is one of the most widely used recreational substances, and is also one of the most commonly used substances reported by individuals in the general community and entering drug treatment services. Perhaps relatedly, the potency of cannabis products has been found to be increasing across Europe and elsewhere, which may increase the risk of harm as some believe higher potency predicts poorer neurobehavioral outcomes. Little is known about vulnerability factors that may increase the risk of cannabis use onset and developing cannabis-related mental health outcomes. Improved understanding of these issues could help identify those at risk of using cannabis, developing use disorder and associated mental disorders, all of which may inform targeted, evidence-based interventions for prevention, early intervention and treatment.