Mortality and Morbidity in Patients in Opioid Maintenance Treatment

Opioid use disorders (OUD) are associated with high somatic and psychiatric comorbidity, overdose and non-overdose mortality. Opioid maintenance treatment (OMT) is expected to reduce the negative effects OUD. But OMT is not a static treatment modality and the effects of OMT may vary across settings (countries).

We use and compare data from various nationwide health and population registers that are available in Czechia, Norway and Denmark.

We aim to present: crude mortality rates for all cause and cause-specific mortality, somatic and mental comorbidities in OMT patients, other specific differences in various OMT settings, OMT patient populations, and OMT drug (methadone, buprenorphine and buprenorphine with naloxone).

Our long-term goal is to further improve OMT and our understanding of key elements that will further increase the treatment outcomes.